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Epidemiology of sarcomas

The articles in this series focus on sarcoma epidemiology as well as their association with inherited syndromes. Syndromic cancers represent a powerful source of information as they have always provided invaluable insights into the molecular pathogenesis of neoplastic diseases. In this perspective, animal models represent an extremely helpful tool to further elucidate the molecular mechanisms underlying sarcomagenesis.

Exposure to ionizing radiations as a predisposing factor to sarcoma development has understandably been the source of sharp debate to the extent that there exists a strong need to focus on this potential pathogenetic link. It is hoped that this series will not only help in clarifying important aspects of sarcoma biology but also will set the field for further research and scientific debate.

Publication of this thematic series has been supported by funding from the European Union Seventh Framework Programme under grant agreement n°278742 - Eurosarc.

Collection published: 4 October 2012


Review   Open Access

Mouse models of sarcomas: critical tools in our understanding of the pathobiology

Sean M Post Clinical Sarcoma Research 2012, 2:20 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access

Genetically engineered mouse models and human osteosarcoma

Alvin JM Ng, Anthony J Mutsaers, Emma K Baker, Carl R Walkley Clinical Sarcoma Research 2012, 2:19 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access

Sarcoma risk after radiation exposure

Amy Berrington de Gonzalez, Alina Kutsenko, Preetha Rajaraman Clinical Sarcoma Research 2012, 2:18 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access

Malignant peripheral nerve sheath tumours in inherited disease

D Evans, Susan M Huson, Jillian M Birch Clinical Sarcoma Research 2012, 2:17 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access Highly Accessed

Inherited gastrointestinal stromal tumor syndromes: mutations, clinical features, and therapeutic implications

Michael A Postow, Mark E Robson Clinical Sarcoma Research 2012, 2:16 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access

Sarcomas in hereditary retinoblastoma

Ruth A Kleinerman, Sara J Schonfeld, Margaret A Tucker Clinical Sarcoma Research 2012, 2:15 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access Highly Accessed

The Epidemiology of Sarcoma

Zachary Burningham, Mia Hashibe, Logan Spector, Joshua D Schiffman Clinical Sarcoma Research 2012, 2:14 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Open Access

Hereditary and environmental epidemiology of sarcomas

David M Thomas, Sharon A Savage, Gareth L Bond Clinical Sarcoma Research 2012, 2:13 (4 October 2012)

Abstract | Full text | PDF | PubMed


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