The rule of fives, a simple way to stratify risk for primary gastrointestinal stromal tumors (GIST)
Departments of Medicine, Pediatrics, and Orthopaedics, Mount Sinai School of Medicine, New York, NY, 10029-6574, USA
Clinical Sarcoma Research 2012, 2:21 doi:10.1186/2045-3329-2-21Published: 5 October 2012
The current AJCC version 7 staging system is a lugubrious means to classify gastrointestinal stromal tumors with respect to their risk and need for adjuvant systemic therapy. The rule of fives, suggested here, is a means to quickly assess whether a given gastrointestinal stromal tumor is low vs intermediate-high risk.